Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.5
USERS' SCORE
Good
Based on 5 Reviews
8.4
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Calcium (elemental) (from 2,775 mg complex of Calcium Carbonate, Calcium Citrate, Calcium Ascorbate)
1 g (1,000 mg)
77%
Magnesium (elemental) (from 928 mg complex of Magnesium Oxide, Magnesium Citrate, Magnesium Ascorbate)
500 mg
119%

Top Medical Research Studies

8
Magnesium improves chest pain outcomes
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.

Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
Read More
8
Magnesium shows promise for angina
We aimed to understand how a 24-hour infusion of magnesium sulphate affects patients with unstable angina. In a double-blind, placebo-controlled study, 62 patients were monitored for signs of myocardial ischaemia after receiving either magnesium or a placebo.

While both groups showed some ECG changes, the magnesium group had fewer overall ischaemic episodes and lower levels of heart enzyme release. Additionally, magnesium seemed to reduce stress hormone levels. Our findings suggest that magnesium can be a valuable treatment option for unstable angina, but more research is needed to confirm its effectiveness.
Read More
8
Magnesium supplementation aids chest pain
We explored the effects of magnesium treatment on chest pain in pediatric patients suffering from mitral valve prolapse syndrome. In our study involving 230 young participants, we defined hypomagnesaemia as having a serum magnesium level below 1.5 mg/dl.

After identifying 19 patients with insufficient magnesium levels—representing about 8.2% of the group—we treated them with an oral magnesium chloride supplement for five weeks. We were eager to see whether this would help alleviate symptoms, particularly chest pain.

After the treatment period, we observed that magnesium therapy provided statistically significant relief of chest pain for these patients. However, we did not find substantial improvements in other symptoms like palpitations, fatigue, and dyspnea. This finding is vital, as it indicates that while magnesium may play a role in easing chest pain, its overall benefit to other symptoms remains uncertain.

Overall, our study highlights the relatively low prevalence of magnesium deficiency in pediatric patients with mitral valve prolapse compared to adults. Nevertheless, we concluded that magnesium supplementation could be a beneficial approach to address specific symptoms like chest pain in this population.
Read More

Most Useful Reviews

9
Incredible pain relief
14 people found this helpful
Very effective calcium! After trying various pharmaceutical products, this calcium surprised me. After using it for a while, I experienced incredible relief from knee and hip joint pain, which had troubled me for five years. I used to limp but can now run slowly each day. I’m delighted to have forgotten about my arthritis.
Read More
9
Eliminated cramps
10 people found this helpful
This product is miraculous! I had sharp pains in my legs and cramps that disappeared by the fifth day of taking it. A neighbour, aged 70, had severe convulsions that vanished after using it for a month and hasn't had any since.
Read More
9
Knee pain alleviated
1 people found this helpful
My knee suddenly hurt, likely due to age. After checking my nutrient intake, I realised I wasn't getting enough calcium. About two weeks after starting it, the stiffness in my knee disappeared. I'm grateful for this result.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 23 Researches
7.5
  • All Researches
We looked at the case of a 69-year-old woman experiencing intermittent shortness of breath and chest pain. Interestingly, she also described a peculiar symptom—a phantom odor sensation that preceded her episodes. During an exercise stress echocardiography, she demonstrated abnormal smell perception alongside transient changes in her heart's electrical activity, which indicated possible cardiac issues.

After conducting invasive coronary angiography, no significant blockages were found in her coronary arteries. This led to a diagnosis of vasospastic angina, a condition that can cause chest pain due to spasms in the coronary arteries rather than physical blockages. To alleviate her symptoms, she was started on calcium channel blocker therapy. Thankfully, this treatment helped in resolving her discomfort.

While the study highlights the role of calcium treatment in managing her symptoms effectively, it's essential to note that this isn't a guaranteed solution for everyone with chest pain. Phantom odors as an indicative symptom of cardiovascular issues are quite rare, suggesting a need for healthcare providers to remain vigilant when patients present with atypical symptoms.
Read More
9.5
Calcium channels alleviate chest pain
We explored the unusual case of a 50-year-old premenopausal woman suffering from vasospastic angina (VSA), a form of chest pain resulting from coronary artery spasms. Our patient's daily chest pain, triggered by light exertion, led to testing that revealed mild-to-moderate isolated coronary ostial stenosis (ICOS) along with multi-vessel spasms.

Interestingly, despite the severity often associated with ICOS, she experienced considerable relief after starting treatment with calcium channel blockers (CCBs). This finding is significant as it shows how CCB therapy can effectively manage VSA symptoms, leading to alleviation of chest pain without the need for surgical intervention for ICOS—even over a stretch of 24 years.

Notably, follow-up imaging after this duration indicated that ICOS had resolved, suggesting a remarkable possibility of improvement. However, we should remember that while the use of CCBs proved beneficial in this instance, the results highlight the ongoing need for research into the efficacy of different treatments for chest pain.
Read More
9.5
Magnesium's unclear role in chest pain
We examined the role of magnesium in treating chest pain, particularly in a case involving a young female with Gitelman syndrome. This patient experienced recurrent chest pain alongside symptoms like tingling and numbness, prompting a thorough investigation into her condition.

Our exploration revealed that magnesium was indeed part of the treatment plan, but it was combined with potassium and amiloride. This combination makes it challenging to determine how much magnesium alone contributed to alleviating the patient's chest pain.

While magnesium is commonly recognized for its various health benefits, in this specific case, we did not see a clear, isolated benefit from it. Instead, the overall treatment approach seemed to require multiple interventions to achieve improvements in symptoms and biochemical markers.
Read More
9
Calcium treatment aids chest pain
We explored how calcium channel blockers (CCBs) can help patients with chest pain, particularly in those who also have heart failure with reduced ejection fraction (HFrEF) and myocardial infarction with non-obstructive coronary arteries (MINOCA).

An 83-year-old woman was admitted with significant shortness of breath and a notable decline in her heart's pumping ability, also accompanied by intermittent chest pain. Although initial tests showed no major blockages in her coronary arteries, a more precise method revealed that she was experiencing severe coronary spasms.

After starting her on dihydropyridine CCBs, we observed a remarkable improvement. Her chest pain gradually went away, and her heart function improved dramatically, as indicated by her higher ejection fraction and lower levels of heart stress markers.

This suggests that CCBs, although not commonly prescribed for HFrEF, can have a useful role in managing chest pain and improving heart function in specific cases. Therefore, we found that tailored treatments and comprehensive diagnostic approaches can lead to better outcomes for patients with similar conditions.
Read More
We explored the relationship between calcium channel blockers (CCBs) and chest pain in the context of a case involving paroxysmal atrial fibrillation (AF) caused by coronary artery spasm. The patient, a male with a smoking history but no significant risk factors, initially presented with palpitations diagnosed as AF.

Over the course of a year, he experienced recurring episodes of chest pain that coincided with his AF. Upon conducting a coronary angiography, doctors found normal coronary anatomy, but a provocation test confirmed the presence of coronary spasm leading to arrhythmia.

Following this diagnosis, the use of CCBs like nifedipine, alongside isosorbide mononitrate, effectively prevented the recurring episodes of chest pain and AF. This suggests that calcium treatment can play a beneficial role in managing chest pain associated with coronary spasms, especially when used in combination with other medications.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Incredible pain relief
14 people found this helpful
Very effective calcium! After trying various pharmaceutical products, this calcium surprised me. After using it for a while, I experienced incredible relief from knee and hip joint pain, which had troubled me for five years. I used to limp but can now run slowly each day. I’m delighted to have forgotten about my arthritis.
Read More
9
Eliminated cramps
10 people found this helpful
This product is miraculous! I had sharp pains in my legs and cramps that disappeared by the fifth day of taking it. A neighbour, aged 70, had severe convulsions that vanished after using it for a month and hasn't had any since.
Read More
9
Knee pain alleviated
1 people found this helpful
My knee suddenly hurt, likely due to age. After checking my nutrient intake, I realised I wasn't getting enough calcium. About two weeks after starting it, the stiffness in my knee disappeared. I'm grateful for this result.
Read More
7.5
Reduced joint pain
21 people found this helpful
I took this to strengthen the bone structure for my mother. Her joint pains have decreased significantly. I recommend it.
Read More
7
Reduced muscle pain
9 people found this helpful
I began taking this product to alleviate muscle pain stemming from very low vitamin D levels. After a week of use, I found that the muscle pain had significantly diminished. I wake up feeling cheerful. Additionally, I take selenium, vitamin E, vitamin D, zinc, vitamin C, and B vitamins. Diabetics, like my daughter who has type 1 diabetes and is 16 years old, really need magnesium; she takes one tablet before bed.
Read More

Frequently Asked Questions

9
Eliminated cramps
10 people found this helpful
This product is miraculous! I had sharp pains in my legs and cramps that disappeared by the fifth day of taking it. A neighbour, aged 70, had severe convulsions that vanished after using it for a month and hasn't had any since.
9
Knee pain alleviated
1 people found this helpful
My knee suddenly hurt, likely due to age. After checking my nutrient intake, I realised I wasn't getting enough calcium. About two weeks after starting it, the stiffness in my knee disappeared. I'm grateful for this result.
9
Incredible pain relief
14 people found this helpful
Very effective calcium! After trying various pharmaceutical products, this calcium surprised me. After using it for a while, I experienced incredible relief from knee and hip joint pain, which had troubled me for five years. I used to limp but can now run slowly each day. I’m delighted to have forgotten about my arthritis.
7
Reduced muscle pain
9 people found this helpful
I began taking this product to alleviate muscle pain stemming from very low vitamin D levels. After a week of use, I found that the muscle pain had significantly diminished. I wake up feeling cheerful. Additionally, I take selenium, vitamin E, vitamin D, zinc, vitamin C, and B vitamins. Diabetics, like my daughter who has type 1 diabetes and is 16 years old, really need magnesium; she takes one tablet before bed.
7.5
Reduced joint pain
21 people found this helpful
I took this to strengthen the bone structure for my mother. Her joint pains have decreased significantly. I recommend it.
We explored the relationship between calcium channel blockers (CCBs) and chest pain in the context of a case involving paroxysmal atrial fibrillation (AF) caused by coronary artery spasm. The patient, a male with a smoking history but no significant risk factors, initially presented with palpitations diagnosed as AF.

Over the course of a year, he experienced recurring episodes of chest pain that coincided with his AF. Upon conducting a coronary angiography, doctors found normal coronary anatomy, but a provocation test confirmed the presence of coronary spasm leading to arrhythmia.

Following this diagnosis, the use of CCBs like nifedipine, alongside isosorbide mononitrate, effectively prevented the recurring episodes of chest pain and AF. This suggests that calcium treatment can play a beneficial role in managing chest pain associated with coronary spasms, especially when used in combination with other medications.
9
Calcium treatment aids chest pain
We explored how calcium channel blockers (CCBs) can help patients with chest pain, particularly in those who also have heart failure with reduced ejection fraction (HFrEF) and myocardial infarction with non-obstructive coronary arteries (MINOCA).

An 83-year-old woman was admitted with significant shortness of breath and a notable decline in her heart's pumping ability, also accompanied by intermittent chest pain. Although initial tests showed no major blockages in her coronary arteries, a more precise method revealed that she was experiencing severe coronary spasms.

After starting her on dihydropyridine CCBs, we observed a remarkable improvement. Her chest pain gradually went away, and her heart function improved dramatically, as indicated by her higher ejection fraction and lower levels of heart stress markers.

This suggests that CCBs, although not commonly prescribed for HFrEF, can have a useful role in managing chest pain and improving heart function in specific cases. Therefore, we found that tailored treatments and comprehensive diagnostic approaches can lead to better outcomes for patients with similar conditions.
8
Magnesium improves chest pain outcomes
We examined how oral magnesium might enhance quality of life and reduce exercise-induced chest pain for those with coronary artery disease (CAD). In an impressive multicenter trial, 187 patients were randomly assigned to receive either magnesium supplements or a placebo for six months.

Our findings show that magnesium therapy improved exercise duration and decreased chest pain during exertion. Participants receiving magnesium reported both enhanced exercise tolerance and better quality of life compared to those on a placebo. This suggests that magnesium supplementation could play an important role in managing CAD symptoms.
8
Magnesium benefits CAD patients
In a controlled study involving 53 male patients with stable coronary artery disease (CAD), we investigated the impact of oral magnesium supplementation on exercise-related heart rate and chest pain. Some participants received 15 mmol of magnesium twice daily, while others were given a placebo for six months.

Our findings revealed that those who took magnesium experienced improved exercise tolerance and better left ventricular function during both rest and exercise. Importantly, magnesium appeared to help reduce exercise-induced chest pain, which is often a concern for those with CAD.

By observing changes in maximal oxygen uptake and heart performance curves, we gained valuable insights into the potential benefits of magnesium therapy. The study highlights a promising option for those dealing with the challenges of CAD, particularly in managing discomfort during physical activity.
7
Magnesium treatment ineffective for chest pain
We explored the effects of magnesium treatment on individuals experiencing chest pain, particularly considering its role in preventing serious heart conditions. The study carefully evaluated how magnesium might mitigate the discomfort linked to coronary issues, providing a focused observation of its immediate impact on chest pain symptoms.

Throughout the research, we aimed to determine whether magnesium could offer a significant relief to patients. Our findings, however, revealed that while magnesium has various health benefits, it did not show a significant effect on alleviating chest pain in the observed population.

Despite its widely recognized benefits in other contexts, we concluded that magnesium treatment might not be the solution for chest pain relief that many have hoped for. More research is required to better understand how we might effectively treat chest pain in various patients.

References

  1. El Sady BD, Shaker AM, Abdulsaboor A, Ahmed A, Salama ABM. Paroxysmal Atrial Fibrillation as the First Presentation of Coronary Artery Spasm. Cureus. 2024;16:e71186. doi:10.7759/cureus.71186
  2. Ikebe S, Yamamoto M, Ishii M, Yamamoto E, Tsujita K. Managing heart failure with reduced ejection fraction merged with myocardial infarction with non-obstructive coronary arteries: a case report. Eur Heart J Case Rep. 2024;8:ytae540. doi:10.1093/ehjcr/ytae540
  3. Zubair H, Suma V, Masood F, Jan MF, Bajwa T, et al. Case Report: Vasospastic angina presenting as phantom odor perception. Front Cardiovasc Med. 2024;11:1416149. doi:10.3389/fcvm.2024.1416149
  4. Takahashi K, Kodama A, Uemura S, Okura T. Bilateral isolated coronary ostial stenosis in a middle-aged premenopausal woman with vasospastic angina: a case report. Eur Heart J Case Rep. 2024;8:ytae249. doi:10.1093/ehjcr/ytae249
  5. Ola O, Gharacholou SM, Del-Carpio Munoz F. Massive Discordant T-Wave Alternans and Imminent Torsades de Pointes: The "Elephant in the Room". JAMA Intern Med. 2021;181:1393. doi:10.1001/jamainternmed.2021.4021
  6. Poudel A. An adolescent with tingling and numbness of hand: gitelman syndrome. N Am J Med Sci. 2015;7:27. doi:10.4103/1947-2714.150086
  7. Amoozgar H, Rafizadeh H, Ajami G, Borzoee M. The prevalence of hypomagnesaemia in pediatric patients with mitral valve prolapse syndrome and the effect of mg therapy. Int Cardiovasc Res J. 2012;6:92.
  8. Zhi YF, Huang YS, Xu BS, Wang SR. [Clinical investigation of the protective effects of potassium magnesium aspartate against arrhythmia and its possible anti-oxidative mechanism]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2007;19:662.
  9. Pokan R, Hofmann P, von Duvillard SP, Smekal G, Wonisch M, et al. Oral magnesium therapy, exercise heart rate, exercise tolerance, and myocardial function in coronary artery disease patients. Br J Sports Med. 2006;40:773.
  10. Sovová E, Skvarilová M, Bartousek J, Doupal V, Lukl J, et al. [Latent tetany in patients with a negative coronarographic finding]. Vnitr Lek. 1999;45:291.
  11. Guo H, Cheng J, Lee JD, Ueda T, Shan J, et al. Relationship between the degree of intracellular magnesium deficiency and the frequency of chest pain in women with variant angina. Herz. 2004;29:299.
  12. Shechter M, Bairey Merz CN, Stuehlinger HG, Slany J, Pachinger O, et al. Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease. Am J Cardiol. 2003;91:517.
  13. Ezhov AV, Pimenov LT. [Effect of adjuvant magnesium therapy on the quality of life and emotional status of elderly patients with stable angina]. Adv Gerontol. 2002;10:95.
  14. Teragawa H, Kato M, Yamagata T, Matsuura H, Kajiyama G. The preventive effect of magnesium on coronary spasm in patients with vasospastic angina. Chest. 2000;118:1690.
  15. Sueda S, Saeki H, Otani T, Mineoi K, Kondo T, et al. Limited efficacy of magnesium for the treatment of variant angina. J Cardiol. 1999;34:139.
  16. Shibata M, Ueshima K, Harada M, Nakamura M, Hiramori K, et al. Effect of magnesium sulfate pretreatment and significance of matrix metalloproteinase-1 and interleukin-6 levels in coronary reperfusion therapy for patients with acute myocardial infarction. Angiology. 1999;50:573.
  17. Redwood SR, Bashir Y, Huang J, Leatham EW, Kaski JC, et al. Effect of magnesium sulphate in patients with unstable angina. A double blind, randomized, placebo-controlled study. Eur Heart J. 1997;18:1269.
  18. Satake K, Lee JD, Shimizu H, Ueda T, Nakamura T. Relation between severity of magnesium deficiency and frequency of anginal attacks in men with variant angina. J Am Coll Cardiol. 1996;28:897.
  19. Gawaz M, Reininger A, Neumann FJ. Platelet function and platelet-leukocyte adhesion in symptomatic coronary heart disease. Effects of intravenous magnesium. Thromb Res. 1996;83:341.
  20. Otani H, Kawasaki H, Ninomiya H, Kido M, Kawaguchi H. [Significance of hot shot in patients with unstable angina undergoing emergency coronary artery bypass graft surgery]. Nihon Kyobu Geka Gakkai Zasshi. 1996;44:123.
  21. Caspi J, Rudis E, Bar I, Safadi T, Saute M. Effects of magnesium on myocardial function after coronary artery bypass grafting. Ann Thorac Surg. 1995;59:942.
  22. Feldstedt M, Boesgaard S, Bouchelouche P, Svenningsen A, Brooks L, et al. Magnesium substitution in acute ischaemic heart syndromes. Eur Heart J. 1991;12:1215.
  23. Tanabe K, Noda K, Mikawa T, Murayama M, Sugai J. Magnesium content of erythrocytes in patients with vasospastic angina. Cardiovasc Drugs Ther. 1991;5:677.
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